Template:Tularemia antibiotics

Postexposure Prophylaxis

• Doxycycline 100mg PO q12hrs x 14 days OR
• Ciprofloxacin 500mg PO q12hrs x 10 days

Active Disease

• Streptomycin 1g (15mg/kg) IM q12hrs daily x 10 days (First line) OR
• Gentamicin 5mg/kg/day IV/IM once daily x 10 days OR
• Ciprofloxacin 400mg (15mg/kg) IV q12hrs x 10 days OR
• Doxycycline 100mg (2.2mg/kg) IV q12hrs x 14 days OR
• Chloramphenicol 15mg/kg IV q6hrs x 14 days
• Streptomycin 1g IM q12h x10 days; Maximum dose: 2 g/day (adjust dose based on serum levels)
• Streptomycin 15mg/kg IM q12h x10 days; Maximum dose: 2 g/day (adjust dose based on serum levels)

Pediatric

• Gentamicin 2.5mg/kg IV/IM q8hrs x 10 days
• Doxycycline 2.2mg/kg PO/IV q12hrs x 14 days (max 100mg/dose)
• Ciprofloxacin 15mg/kg PO/IV q12hrs x 10 days (max 500mg PO / 400mg IV)