Hemoglobin

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Background

  • Oxygen-carrying protein in red blood cells
  • Reported on CBC; hemoglobin and hematocrit move in parallel

Normal Values

  • Male: 13.5-17.5 g/dL
  • Female: 12.0-16.0 g/dL

Interpretation

  • Low hemoglobin (anemia): blood loss, hemolysis, decreased production, or dilution
  • In acute hemorrhage, hemoglobin may be initially normal (dilution has not yet occurred); it does not drop until volume equilibration over 6-24 hours
  • Transfusion threshold in most ED patients: Hgb <7 g/dL; consider <8 g/dL for active coronary syndrome[1]
  • Elevated hemoglobin (polycythemia): dehydration, chronic hypoxia, polycythemia vera

See Also

References

  1. ↑ Carson JL, et al. Clinical practice guidelines from the AABB: red blood cell transfusion thresholds and storage. JAMA. 2016; 316(19):2025-2035. PMID 27732721.
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