https://wikem.org/w/index.php?action=history&feed=atom&title=Post-hypoxic_myoclonus 2026-04-19T02:53:03Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Post-hypoxic_myoclonus&diff=370415&oldid=prev 2023-05-17T21:04:55Z

<p><span dir="auto"><span class="autocomment">Background</span></span></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 21:04, 17 May 2023</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l2">Line 2:</td> <td colspan="2" class="diff-lineno">Line 2:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Myoclonus (irregular muscle contractions) after hypoxic brain injury due to [[cardiac arrest]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Myoclonus (irregular muscle contractions) after hypoxic brain injury due to [[cardiac arrest]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Acute: onset within 48h of injury</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>*Acute: onset within 48h of injury</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div>**Post-hypoxic myoclonic status: acute myoclonus lasting &gt;30min</div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div>**Post-<ins style="font-weight: bold; text-decoration: none;">[[</ins>hypoxic<ins style="font-weight: bold; text-decoration: none;">]] </ins>myoclonic status: acute myoclonus lasting &gt;30min</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>***Difficult to control, associated with poor prognosis</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>***Difficult to control, associated with poor prognosis</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>***Occurs in 30-40% of comatose cardiac arrest survivors  </div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>***Occurs in 30-40% of comatose cardiac arrest survivors  </div></td></tr> </table>

Rossdonaldson1 https://wikem.org/w/index.php?title=Post-hypoxic_myoclonus&diff=370414&oldid=prev 2023-05-17T21:04:39Z

<p><span dir="auto"><span class="autocomment">See Also</span></span></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 21:04, 17 May 2023</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l38">Line 38:</td> <td colspan="2" class="diff-lineno">Line 38:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==See Also==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==See Also==</div></td></tr> <tr><td class="diff-marker" data-marker="−"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div> </div></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">*[[Hypoxemia]]</ins></div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br/></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==External Links==</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>==External Links==</div></td></tr> </table>

Rossdonaldson1 https://wikem.org/w/index.php?title=Post-hypoxic_myoclonus&diff=225055&oldid=prev 2019-08-19T17:31:00Z

<p>Created page with &quot;==Background== *Myoclonus (irregular muscle contractions) after hypoxic brain injury due to <a href="/wiki/Cardiac_arrest" class="mw-redirect" title="Cardiac arrest">cardiac arrest</a> *Acute: onset within 48h of injury **Post-hypoxic myoclonic stat...&quot;</p> <p><b>New page</b></p><div>==Background==<br /> *Myoclonus (irregular muscle contractions) after hypoxic brain injury due to [[cardiac arrest]]<br /> *Acute: onset within 48h of injury<br /> **Post-hypoxic myoclonic status: acute myoclonus lasting &gt;30min<br /> ***Difficult to control, associated with poor prognosis<br /> ***Occurs in 30-40% of comatose cardiac arrest survivors <br /> *Chronic: onset days-weeks after cardiac arrest in patients who regained consciousness (AKA Lance-Adams syndrome)<br /> <br /> ==Clinical Features==<br /> *Acute:<br /> **Recent (within 48h) hypoxic brain injury with neuronal necrosis<br /> **Abrupt onset of irregular muscle contractions, focal or generalized<br /> *Post-hypoxic status myoclonus<br /> **Onset usually within 12-24h of injury<br /> **Generalized, multifocal clonus<br /> *Chronic <br /> **Onset days-weeks after arrest<br /> **Awareness preserved<br /> **Typically intention myoclonus<br /> <br /> ==Differential Diagnosis==<br /> *[[Seizure]]<br /> <br /> ==Evaluation==<br /> *EEG (r/o seizure)<br /> *Evaluate for alternative etiologies<br /> <br /> ==Management==<br /> *Acute/status<br /> **Difficult and of limited utility<br /> **Consider [[benzodiazepines]], [[propofol]], [[phenytoin]], [[valproate]]<br /> **Address [[goals of care]] given sign of poor prognosis<br /> *Chronic/lance-adams syndrome<br /> **[[Valproate]], [[clonazepam]], and/or [[levetiracetam]] may help control myoclonus<br /> <br /> ==Disposition==<br /> <br /> <br /> ==See Also==<br /> <br /> <br /> ==External Links==<br /> <br /> <br /> ==References==<br /> &lt;references/&gt;<br /> *LITFL: https://litfl.com/post-hypoxic-myoclonus/<br /> [[Category:Neurology]]</div>

ClaireLewis