Myelophthistic anemia - Revision history

ClaireLewis at 05:00, 1 October 2019

2019-10-01T05:00:03Z

← Older revision		Revision as of 05:00, 1 October 2019
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	==Background==		==Background==
	*Form of normocytic anemia		*Form of normocytic [[anemia]]
	*Associated with infiltrative disorder or bone marrow in the setting of malignancy--leukemia, lymphoma, granuloma		*Associated with infiltrative disorder or bone marrow in the setting of malignancy--[[leukemia]], [[lymphoma]], granuloma

	==Clinical Features==		==Clinical Features==
	*Anemia in patient with history of malignancy		*[[Anemia]] in patient with history of malignancy
	*Pale skin		*Pale skin
	*Tachycardia/hypotension in severe cases		*[[Tachycardia]]/[[hypotension]] in severe cases
	*Hepatosplenomegaly as sign of extra medullary hematopoiesis		*[[hepatomegaly\|Hepatosplenomegaly]] as sign of extra medullary hematopoiesis

	==Differential Diagnosis==		==Differential Diagnosis==
	*Aplastic anemia		*[[Aplastic anemia]]
	*Myelofibrosis		*[[Myelofibrosis]]
	*Acute blood loss anemia		*[[hemorrhage\|Acute blood]] loss anemia
	*Bone marrow suppression		*Bone marrow suppression
	*Anemia of chronic disease		*Anemia of chronic disease
	*Hemolytic anemia		*[[Hemolytic anemia]]

	==Evaluation==		==Evaluation==
	*Requires bone marrow biopsy		*Requires bone marrow biopsy
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	*Identify anemia as emergent or non-emergent		*Identify anemia as emergent or non-emergent
	*Evaluate for superimposed etiologies of anemia (Ie acute blood loss) and target treatment in the ED		*Evaluate for superimposed etiologies of anemia (Ie acute blood loss) and target treatment in the ED
	*If emergent anemia get IV access, transfuse for signs of end organ damage--altered mental status, hypotension, chest pain, shortness of breath, decreased UOP		*If emergent anemia get IV access, [[pRBCs\|transfuse]] for signs of end organ damage--altered mental status, hypotension, chest pain, shortness of breath, decreased UOP
	*Will need treatment of underlying malignancy to allow marrow recovery while supporting hemodynamics		*Will need treatment of underlying malignancy to allow marrow recovery while supporting hemodynamics

Rossdonaldson1: Text replacement - "AMS" to "altered mental status"

2016-07-31T13:21:18Z

Text replacement - "AMS" to "altered mental status"

← Older revision		Revision as of 13:21, 31 July 2016
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	*Identify anemia as emergent or non-emergent		*Identify anemia as emergent or non-emergent
	*Evaluate for superimposed etiologies of anemia (Ie acute blood loss) and target treatment in the ED		*Evaluate for superimposed etiologies of anemia (Ie acute blood loss) and target treatment in the ED
	*If emergent anemia get IV access, transfuse for signs of end organ damage--~~AMS~~, hypotension, chest pain, shortness of breath, decreased UOP		*If emergent anemia get IV access, transfuse for signs of end organ damage--altered mental status, hypotension, chest pain, shortness of breath, decreased UOP
	*Will need treatment of underlying malignancy to allow marrow recovery while supporting hemodynamics		*Will need treatment of underlying malignancy to allow marrow recovery while supporting hemodynamics

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-23T01:00:07Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

← Older revision		Revision as of 01:00, 23 July 2016
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	*Anemia of chronic disease		*Anemia of chronic disease
	*Hemolytic anemia		*Hemolytic anemia
	==~~Diagnosis~~==		==Evaluation==
	*Requires bone marrow biopsy		*Requires bone marrow biopsy
	*Labs show normocytic anemia with decreased reticulocyte count		*Labs show normocytic anemia with decreased reticulocyte count

ClaireLewis: /* Clinical Features */

2016-07-14T01:54:54Z

Clinical Features

← Older revision		Revision as of 01:54, 14 July 2016
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	*Associated with infiltrative disorder or bone marrow in the setting of malignancy--leukemia, lymphoma, granuloma		*Associated with infiltrative disorder or bone marrow in the setting of malignancy--leukemia, lymphoma, granuloma
	==Clinical Features==		==Clinical Features==
	*Anemia in patient with ~~h/o~~ malignancy		*Anemia in patient with history of malignancy
	*Pale skin		*Pale skin
	*Tachycardia/hypotension in severe cases		*Tachycardia/hypotension in severe cases

Neil.m.young: Text replacement - "==Sources==" to "==References=="

2016-06-26T11:47:43Z

Text replacement - "==Sources==" to "==References=="

← Older revision		Revision as of 11:47, 26 June 2016
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	*[[Anemia]]		*[[Anemia]]

	==~~Sources~~==		==References==
	*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "Anemia". Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.		*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "Anemia". Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.
	<references/>		<references/>

	[[Category:Heme/Onc]]		[[Category:Heme/Onc]]

Zipdoc at 13:31, 18 August 2015

2015-08-18T13:31:30Z

← Older revision		Revision as of 13:31, 18 August 2015
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	*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "Anemia". Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.		*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "Anemia". Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.
	<references/>		<references/>

			[[Category:Heme/Onc]]

Zipdoc: reference

2015-08-17T20:19:17Z

reference

← Older revision		Revision as of 20:19, 17 August 2015
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	==Sources==		==Sources==
	*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "~~Smallpox~~." Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.		*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "Anemia". Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.
	<references/>		<references/>

Zipdoc at 20:18, 17 August 2015

2015-08-17T20:18:33Z

← Older revision		Revision as of 20:18, 17 August 2015
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	==Sources==		==Sources==
			*Rosen, Peter, John A. Marx, Robert S. Hockberger, and Ron M. Walls. "Smallpox." Rosen's Emergency Medicine Concepts and Clinical Practice. 8th ed. Vol. 2. Philadelphia, PA: Elsevier/Saunders, 2013.
	<references/>		<references/>

Zipdoc at 20:16, 17 August 2015

2015-08-17T20:16:00Z

← Older revision		Revision as of 20:16, 17 August 2015
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	==Background==		==Background==
	*Form of normocytic anemia		*Form of normocytic anemia
	*~~Infiltrative~~ disorder of bone marrow in the setting of malignancy--~~invasive tumor,~~ leukemia, lymphoma, granuloma		*Associated with infiltrative disorder or bone marrow in the setting of malignancy--leukemia, lymphoma, granuloma

	==Clinical Features==		==Clinical Features==
	*~~Most pts begin to be symptomatic at ~7gm~~/dL		*Anemia in patient with h/o malignancy
	*~~Weakness, fatigue, lethargy, DOE, palpitations~~		*Pale skin
	*Skin, nail bed, mucosal pallor
	*Widened pulse pressure
	*Tachycardia/hypotension in severe cases		*Tachycardia/hypotension in severe cases
	*Hepatosplenomegaly as sign of extra medullary hematopoiesis		*Hepatosplenomegaly as sign of extra medullary hematopoiesis

	==Differential Diagnosis==		==Differential Diagnosis==
	{{Anemia ~~DDX}}~~		*Aplastic anemia
			*Myelofibrosis
			*Acute blood loss anemia
			*Bone marrow suppression
			*Anemia of chronic disease
			*Hemolytic anemia
	==Diagnosis==		==Diagnosis==
	*Requires bone marrow biopsy		*Requires bone marrow biopsy
	*Labs show normocytic anemia with decreased reticulocyte count		*Labs show normocytic anemia with decreased reticulocyte count
	*Exam with signs of extra medullary hematopoiesis		*Exam with signs of extra medullary hematopoiesis
	*Index of suspicion in setting of malignancy ~~+ anemia~~		*Index of suspicion in setting of malignancy

	==Management==		==Management==
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	==See Also==		==See Also==
	*[[Anemia]]		*[[Anemia]]
	*[[Transfusions]]

	~~==External Links==~~

	==~~References~~==		==Sources==
	<references/>		<references/>

	~~[[Category:Heme/Onc]]~~

Mholtz at 00:28, 4 August 2015

2015-08-04T00:28:20Z

← Older revision		Revision as of 00:28, 4 August 2015
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	==Differential Diagnosis==		==Differential Diagnosis==
	*Aplastic anemia		{{Anemia DDX}}
	*Myelofibrosis
	*Acute blood loss anemia
	*Bone marrow suppression
	*Anemia ~~of chronic disease~~
	*Hemolytic anemia

	==Diagnosis==		==Diagnosis==
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	==References==		==References==
	<references/>		<references/>

			[[Category:Heme/Onc]]