Lithium - Revision history

Danbot: Switch SMW query from broadtable to table format for better layout with TOC

2026-03-20T21:58:30Z

Switch SMW query from broadtable to table format for better layout with TOC

← Older revision		Revision as of 21:58, 20 March 2026
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	\|?Has Route=Route		\|?Has Route=Route
	\|?Has Population=Population		\|?Has Population=Population
	\|format=~~broadtable~~		\|format=table
	\|headers=plain		\|headers=plain
	\|mainlabel=-		\|mainlabel=-

Danbot: Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

2026-03-20T17:26:15Z

Fix SMW query: replace link=subject with mainlabel=- to fix broken subobject fragment links

← Older revision		Revision as of 17:26, 20 March 2026
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	\|format=broadtable		\|format=broadtable
	\|headers=plain		\|headers=plain
	\|~~link~~=~~subject~~		\|mainlabel=-
	\|sort=Has Indication		\|sort=Has Indication
	\|limit=50		\|limit=50

Danbot: Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

2026-03-20T16:44:25Z

Add dynamic SMW Indications by Condition table (auto-populated from disease pages via MedicationDose template)

← Older revision		Revision as of 16:44, 20 March 2026
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	==Comments==		==Comments==


			==Indications by Condition==
			''The following table is automatically generated from disease/condition pages across WikEM.''

			{{#ask:[[Has DrugName::Lithium]]
			\|?Has Indication=Indication
			\|?Has Dose=Dose
			\|?Has Context=Context
			\|?Has Route=Route
			\|?Has Population=Population
			\|format=broadtable
			\|headers=plain
			\|link=subject
			\|sort=Has Indication
			\|limit=50
			}}

	==See Also==		==See Also==

ClaireLewis: /* References */

2019-09-22T22:56:35Z

References

← Older revision		Revision as of 22:56, 22 September 2019
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	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:Psychiatry]]

ClaireLewis at 16:29, 19 September 2019

2019-09-19T16:29:10Z

← Older revision		Revision as of 16:29, 19 September 2019
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	==Administration==		==Administration==
	*Type:		*Type: Anti[[bipolar disorder\|manic]] agent
	*Dosage Forms:		*Dosage Forms:
	*Routes of Administration: oral		*Routes of Administration: oral
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	*[[Lactation risk categories\|Lactation risk]]: infant risk cannot be ruled out		*[[Lactation risk categories\|Lactation risk]]: infant risk cannot be ruled out
	===Renal Dosing===		===Renal Dosing===
	*Adult:		*Adult: Contraindicated if renal function unstable<ref>https://reference.medscape.com/drug/eskalith-lithobid-lithium-342934#5</ref>
	*Pediatric:
	===Hepatic Dosing===		===Hepatic Dosing===
	*Adult:		*Adult: Not established
	*Pediatric:

	==Contraindications==		==Contraindications==
	*Allergy to class/drug		*Allergy to class/drug
	*~~Dehydration, cardiovascular disease, sodium~~ depletion~~, concurrent~~ diuretics~~, renal~~ disease~~: needs inpatient monitoring if treatment required~~		*Unstable renal function
			*Severe dehydration
			*Sodium depletion
			*Severe debilitation
			*Concurrent diuretics
			*Severe cardiovascular disease
			*1st trimester pregnancy

	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
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	===Common===		===Common===
	*~~Hypothroidism~~, weight gain		*Hypothyroidism, weight gain
	*Nephrotoxicity		*Nephrotoxicity
	*Fine tremor, hyperreflexia		*Fine tremor, hyperreflexia
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	==Mechanism of Action==		==Mechanism of Action==
			*Exact mechanism unclear; inhibits postsynaptic D2 receptor supersensitivity, alters cation transport in nerve cells, influences serotonin/norepinephrine reuptake, inhibits phosphatidylinositol cycle second messenger systems<ref>https://reference.medscape.com/drug/eskalith-lithobid-lithium-342934#5</ref>

	==Comments==		==Comments==

Kxl328: /* Serious */

2018-02-26T12:50:32Z

Serious

← Older revision		Revision as of 12:50, 26 February 2018
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	==Adverse Reactions==		==Adverse Reactions==
	===Serious===		===Serious===
	*Toxicity (see [[Lithium toxicity]]		*Toxicity (see [[Lithium toxicity]])
	*Seizure, ataxia, raised ICP		*Seizure, ataxia, raised ICP
	*Angioedema		*Angioedema
	*Erythema multiforme		*Erythema multiforme

	===Common===		===Common===
	*Hypothroidism, weight gain		*Hypothroidism, weight gain

Neil.m.young: Text replacement - "0 mg" to "0mg"

2016-07-26T09:10:53Z

Text replacement - "0 mg" to "0mg"

← Older revision		Revision as of 09:10, 26 July 2016
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	==Adult Dosing==		==Adult Dosing==
	*Maintenance: ~~300 mg~~ PO 3 to 4 times daily; desired serum lithium level 0.6 to 1.2 mEq/L		*Maintenance: 300mg PO 3 to 4 times daily; desired serum lithium level 0.6 to 1.2 mEq/L
	*Acute manic episode: ~~600 mg~~ PO 3 times daily; desired serum lithium level 1 to 1.5 mEq/L		*Acute manic episode: 600mg PO 3 times daily; desired serum lithium level 1 to 1.5 mEq/L
	==Pediatric Dosing==		==Pediatric Dosing==
	''Safety/efficacy not established in children <12yo''		''Safety/efficacy not established in children <12yo''

ClaireLewis at 03:24, 14 July 2016

2016-07-14T03:24:23Z

← Older revision		Revision as of 03:24, 14 July 2016
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	~~#REDIRECT~~[[Lithium toxicity]]		==Administration==
			*Type:
			*Dosage Forms:
			*Routes of Administration: oral
			*Common Trade Names:

			==Adult Dosing==
			*Maintenance: 300 mg PO 3 to 4 times daily; desired serum lithium level 0.6 to 1.2 mEq/L
			*Acute manic episode: 600 mg PO 3 times daily; desired serum lithium level 1 to 1.5 mEq/L
			==Pediatric Dosing==
			''Safety/efficacy not established in children <12yo''
			==Special Populations==
			*[[Drug Ratings in Pregnancy\|Pregnancy Rating]]: D
			*[[Lactation risk categories\|Lactation risk]]: infant risk cannot be ruled out
			===Renal Dosing===
			*Adult:
			*Pediatric:
			===Hepatic Dosing===
			*Adult:
			*Pediatric:

			==Contraindications==
			*Allergy to class/drug
			*Dehydration, cardiovascular disease, sodium depletion, concurrent diuretics, renal disease: needs inpatient monitoring if treatment required
			==Adverse Reactions==
			===Serious===
			*Toxicity (see [[Lithium toxicity]]
			*Seizure, ataxia, raised ICP
			*Angioedema
			*Erythema multiforme
			===Common===
			*Hypothroidism, weight gain
			*Nephrotoxicity
			*Fine tremor, hyperreflexia
			*Leukocytosis
			*Nausea, gastritis
			*Acne


			==Pharmacology==
			*Half-life: 14-50hr
			*Metabolism: Renal
			*Excretion: Renal

			==Mechanism of Action==

			==Comments==

			==See Also==
			*[[Lithium toxicity]]
			==References==
			<references/>
			[[Category:Pharmacology]]

Neil.m.young: double redirect

2015-06-22T13:43:17Z

double redirect

← Older revision		Revision as of 13:43, 22 June 2015
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	#REDIRECT[[Lithium ~~Toxicity~~]]		#REDIRECT[[Lithium toxicity]]

Rossdonaldson1: Redirected page to Lithium Toxicity

2013-09-26T17:42:09Z

Redirected page to Lithium Toxicity

New page

#REDIRECT[[Lithium Toxicity]]