Levonorgestrel - Revision history

ClaireLewis: /* References */

2019-09-22T22:54:16Z

References

← Older revision		Revision as of 22:54, 22 September 2019
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	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]
			[[Category:OBGYN]]

Bmurray990: /* Administration */

2019-01-26T21:23:01Z

Administration

← Older revision		Revision as of 21:23, 26 January 2019
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	==Administration==		==Administration==
	*Type: Contraceptive		*Type: Contraceptive
	*Dosage Forms:		*Dosage Forms: Tablet 0.75mg, 1.5mg
	*Routes of Administration: oral, intrauterine (IUD)		*Routes of Administration: oral, intrauterine (IUD)
	*Common Trade Names: Plan-B, most brands of combination OCPs, Mirena		*Common Trade Names: Plan-B, most brands of combination OCPs, Mirena

Mholtz: Text replacement - "OR" to "'''OR'''"

2017-05-30T21:14:57Z

Text replacement - "OR" to "'''OR'''"

← Older revision		Revision as of 21:14, 30 May 2017
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	==Adult Dosing==		==Adult Dosing==
	*[[Emergency contraception]]: 0.75mg PO q12 x 2 OR 1.5mg PO once, as soon as possible within 72 hours of unprotected sex		*[[Emergency contraception]]: 0.75mg PO q12 x 2 '''OR''' 1.5mg PO once, as soon as possible within 72 hours of unprotected sex

	==Pediatric Dosing==		==Pediatric Dosing==

Ostermayer: Text replacement - "DVT" to "DVT"

2017-01-27T20:28:56Z

Text replacement - "*DVT" to "*DVT"

← Older revision		Revision as of 20:28, 27 January 2017
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	===Serious===		===Serious===
	*Pills:		*Pills:
	**DVT/PE, stroke, MI		**[[DVT]]/PE, stroke, MI
	**Depression, suicidality		**Depression, suicidality
	*IUDs:		*IUDs:

ClaireLewis: Created page with "==Administration== Type: Contraceptive Dosage Forms: Routes of Administration: oral, intrauterine (IUD) Common Trade Names: Plan-B, most brands of combination OCPs, Mirena..."

2016-11-14T04:17:42Z

Created page with "==Administration== *Type: Contraceptive *Dosage Forms: *Routes of Administration: oral, intrauterine (IUD) *Common Trade Names: Plan-B, most brands of combination OCPs, Mirena..."

New page

==Administration==
*Type: Contraceptive
*Dosage Forms:
*Routes of Administration: oral, intrauterine (IUD)
*Common Trade Names: Plan-B, most brands of combination OCPs, Mirena

==Adult Dosing==
*[[Emergency contraception]]: 0.75mg PO q12 x 2 OR 1.5mg PO once, as soon as possible within 72 hours of unprotected sex

==Pediatric Dosing==
*See above

==Special Populations==
*[[Drug Ratings in Pregnancy|Pregnancy Rating]]: X
*[[Lactation risk categories|Lactation risk]]: Infant risk cannot be ruled out
*Renal Dosing: no adjustment
*Hepatic dosing: no adjustment

==Contraindications==
*Allergy to class/drug
*Pregnancy
*IUDs only:
**Active pelvic infection or STD
**Immunocompromise
**Known or suspected breast, uterine, or cervical cancer
**Acute liver disease or liver tumor
**Structural uterine anomaly including fibroids that distort uterine cavity

==Adverse Reactions==
===Serious===
*Pills:
**DVT/PE, stroke, MI
**Depression, suicidality
*IUDs:
**Ectopic pregnancy
**Uterine perforation
**PID, sepsis
===Common===
*Nausea, abdominal pain
*Headache, dizziness
*Abnormal vaginal bleeding, breast tenderness, ovarian cysts
*Pills:
**Acne
**Fatigue
*IUDs:
**Pelvic pain, vulvovaginitis
**Irregular menses, hypomenorrhea/amenorrhea

==Pharmacology==
*Half-life: Oral: 17-27.5h
*Metabolism: Hepatic, primarily via CYP3A4
*Excretion: Renal, fecal

==Mechanism of Action==
*Progestogen; inhibits ovulation or fertilization by altering tubal transport of sperm and/or ova

==Comments==

==See Also==
*[[Emergency contraception]]
*[[IUD]]

==References==
<references/>
[[Category:Pharmacology]]