https://wikem.org/w/index.php?action=history&feed=atom&title=Colestipol%2Fen 2026-04-19T00:47:09Z Revision history for this page on the wiki MediaWiki 1.38.2 https://wikem.org/w/index.php?title=Colestipol/en&diff=380868&oldid=prev 2026-01-07T13:59:23Z

<p>Updating to match new version of source page</p> <p><b>New page</b></p><div>&lt;languages/&gt;<br /> <br /> ==Administration==<br /> <br /> *Type: Bile Acid Binder<br /> *Dosage Forms: 1 g tab; 5 g/scoop granules; 5 g granule packet<br /> *Routes of Administration: Oral<br /> *Common Trade Names: N/A<br /> <br /> <br /> ==Adult Dosing==<br /> <br /> *[[Special:MyLanguage/Digoxin toxicity|Digoxin toxicity]], adjunct tx<br /> **Granules: 5 g PO q6-8h<br /> ***Start: 10 g PO x1 within 1-3h after last oral digoxin ingestion<br /> ***Max: 30 g/day<br /> *Gallbladder surgery-associated [[Special:MyLanguage/diarrhea|diarrhea]], adjunct tx<br /> **Tabs: 2-16 g/day PO divided QD-QID<br /> ***Start: 2 g PO QD-bid<br /> ***Max: 16 g/day.<br /> ***Do not crush/cut/chew<br /> **Granules:5-30 g/day PO divided QD-QID<br /> ***Start: 5 g PO QD-bid<br /> ***Max: 30 g/day<br /> *Hypercholesterolemia<br /> **Tabs: 2-16 g/day PO divided QD-QID<br /> ***Start: 2 g PO QD-bid<br /> ***Max: 16 g/day.<br /> ***Do not crush/cut/chew<br /> **Granules:5-30 g/day PO divided QD-QID<br /> ***Start: 5 g PO QD-bid<br /> ***Max: 30 g/day<br /> *[[Special:MyLanguage/Pruritus|Pruritus]] secondary to biliary obstruction<br /> **Tabs: 2-16 g/day PO divided QD-QID<br /> ***Start: 2 g PO QD-bid<br /> ***Max: 16 g/day.<br /> ***Do not crush/cut/chew<br /> **Granules:5-30 g/day PO divided QD-QID<br /> ***Start: 5 g PO QD-bid<br /> ***Max: 30 g/day<br /> <br /> <br /> ==Pediatric Dosing==<br /> <br /> Pediatric dosing currently unavailable.<br /> <br /> <br /> ==Special Populations==<br /> <br /> *[[Special:MyLanguage/Drug pregnancy categories|Pregnancy Rating]]: C; Inadequate data to assess risk<br /> *Lactation risk: L3; Safety unknown<br /> <br /> <br /> ===Renal Dosing===<br /> <br /> *Adult: No adjustment<br /> *Pediatric: N/A<br /> <br /> ===Hepatic Dosing===<br /> <br /> *Adult: Not defined.<br /> *Pediatric: N/A<br /> <br /> <br /> ==Contraindications==<br /> <br /> *Allergy to class/drug<br /> *Caution if constipation<br /> *Caution if prolonged use<br /> <br /> <br /> ==Adverse Reactions==<br /> <br /> <br /> ===Serious===<br /> <br /> *Fecal impaction<br /> *[[Special:MyLanguage/PUD|PUD]]<br /> *[[Special:MyLanguage/Cholecystitis|Cholecystitis]]<br /> *[[Special:MyLanguage/Cholelithiasis|Cholelithiasis]]<br /> *Esophageal obstruction<br /> <br /> <br /> ===Common===<br /> <br /> *[[Special:MyLanguage/Constipation|Constipation]]<br /> *Abdominal pain<br /> *Abdominal cramps<br /> *Abdominal distention<br /> *Flatulence<br /> *[[Special:MyLanguage/Dyspepsia|Dyspepsia]]<br /> *Loose stool/[[Special:MyLanguage/Diarrhea|Diarrhea]]<br /> *[[Special:MyLanguage/Nausea|Nausea]]/[[Special:MyLanguage/Vomiting|Vomiting]]<br /> *ALT, AST elevation<br /> *Alk Phos. elevation<br /> *Bleeding [[Special:MyLanguage/hemorrhoids|hemorrhoids]]<br /> <br /> <br /> ==Pharmacology==<br /> <br /> *Half-life: Unknown<br /> *Metabolism: N/A<br /> *Excretion: Feces<br /> <br /> <br /> ==Mechanism of Action==<br /> <br /> Binds intestinal bile acids for excretion.<br /> <br /> <br /> ==Comments==<br /> <br /> <br /> ==See Also==<br /> <br /> [[Special:MyLanguage/Digoxin toxicity|Digoxin toxicity]]<br /> <br /> <br /> ==References==<br /> <br /> &lt;references/&gt;<br /> <br /> [[Category:Pharmacology]]<br /> [[Category:GI]]<br /> [[Category:Toxicology]]</div>

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