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Capsaicin - Revision history
2026-04-18T12:07:38Z
Revision history for this page on the wiki
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ClaireLewis: Created page with "==Administration== *Type: Topical analgesic *Dosage Forms: *Routes of Administration: Topical *Common Trade Names: ==Adult Dosing== *Apply to affected area TID or QID ==Ped..."
2019-09-24T03:34:29Z
<p>Created page with "==Administration== *Type: Topical analgesic *Dosage Forms: *Routes of Administration: Topical *Common Trade Names: ==Adult Dosing== *Apply to affected area TID or QID ==Ped..."</p>
<p><b>New page</b></p><div>==Administration==<br />
*Type: Topical analgesic<br />
*Dosage Forms:<br />
*Routes of Administration: Topical<br />
*Common Trade Names: <br />
<br />
==Adult Dosing==<br />
*Apply to affected area TID or QID<br />
<br />
==Pediatric Dosing==<br />
''Not approved for pediatric use''<br />
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==Special Populations==<br />
===[[Drug pregnancy categories|Pregnancy Rating]]===<br />
*Category B<br />
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===Lactation risk===<br />
*Unknown if absorbed and excreted in milk. DO NOT apply to nipple!<br />
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===Renal Dosing===<br />
*Not established<br />
===Hepatic Dosing===<br />
*Not established<br />
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==Contraindications==<br />
*Allergy to class/drug<br />
*Application to broken or infected skin<br />
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==Adverse Reactions==<br />
===Serious===<br />
<br />
===Common===<br />
*Transient increased pain at application site (dissipates w/ continued use)<br />
*Application site erythema<br />
*Pain<br />
*Nausea/vomiting<br />
*Rash, dryness pruritus, edema, exfoliation, skin odor<br />
*Hypertension<br />
*Sinusitis, bronchitis, cough<br />
*Dizziness, Headache<br />
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==Pharmacology==<br />
*Half-life: <br />
*Metabolism: <br />
*Excretion: <br />
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==Mechanism of Action==<br />
* "Transient receptor potential vanilloid-1 (TRPV1) agonist; topical application causes initial TRPV1 stimulation that may cause pain, followed by pain relief by reduction in TRPV1-expressing nociceptive nerve endings"<ref>https://reference.medscape.com/drug/capzasin-p-zostrix-capsaicin-topical-999316#10</ref><br />
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==Comments==<br />
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==See Also==<br />
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==References==<br />
<references/><br />
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[[Category:Pharmacology]]</div>
ClaireLewis