Ampicillin/Sulbactam - Revision history

Danbot: Remove disease-specific entries now covered by AntibioticDose (3 sections)

2026-03-20T11:07:56Z

Remove disease-specific entries now covered by AntibioticDose (3 sections)

← Older revision		Revision as of 11:07, 20 March 2026
Line 11:		Line 11:
	*Max: 12g/day		*Max: 12g/day

	~~===[[UTI]], [[Pyelonephritis]]===~~
	*3g IM/IV q6 hours x 14 days

	==Pediatric Dosing (<40kg)==		==Pediatric Dosing (<40kg)==
Line 27:		Line 25:
	**Max: 2000mg ampicillin (3000mg Unasyn) per DOSE		**Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

	~~===[[Meningitis]]===~~
	*400mg ampicillin/kg/day IM/IV divided q6 hours
	*First Dose: 100mg ampicillin/kg IM/IV x 1 (150mg Unasyn/kg IM/IV x 1)
	*Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

	~~===[[SSTI]]===~~
	*200mg ampicillin/kg/day IM/IV divided q6 hours

Danbot: Remove disease-specific dosing covered by dynamic SMW tables

2026-03-20T02:57:33Z

Remove disease-specific dosing covered by dynamic SMW tables

@@ Line 10: / Line 10: @@
 *1.5-3g IV/IM q6 hours
 *Max: 12g/day
 ===[[UTI]], [[Pyelonephritis]]===
@@ Line 48: / Line 31: @@
 *First Dose: 100mg ampicillin/kg IM/IV x 1 (150mg Unasyn/kg IM/IV x 1)
 *Max: 2000mg ampicillin (3000mg Unasyn) per DOSE
 ===[[SSTI]]===

Danbot: Restore original dosing content alongside dynamic SMW tables

2026-03-20T02:37:25Z

Restore original dosing content alongside dynamic SMW tables

← Older revision		Revision as of 02:37, 20 March 2026
Line 7:		Line 7:

	==Adult Dosing==		==Adult Dosing==
			===General===
			*1.5-3g IV/IM q6 hours
			*Max: 12g/day

			===[[Bite]] (for Pasteurella multocida Coverage)===
			*1.5-3g IM/IV q6 hours

			===[[Orbital Cellulitis]]===
			*3g IM/IV q6 hours

			===[[Diabetic Foot]] Osteomyelitis<ref>Lipsky, 2004</ref>===
			*3g IM/IV q6 hours

			===[[PID]]===
			*3g IM/IV q6 hours + [[doxycycline]]

			===[[Pneumonia]]===
			*Aspiration or CAP
			**1.5-3g IM/IV q6 hours
			*Hospital-acquired: 3g IM/IV q6 hours

			===[[UTI]], [[Pyelonephritis]]===
			*3g IM/IV q6 hours x 14 days

			==Pediatric Dosing (<40kg)==
			'''Unasyn (ampicillin/sulbactam) is formulated at a 2:1 ratio (3g vial = 2g ampicillin + 1g sulbactam)'''

			===General===
			*'''Mild-moderate'''<ref>Red Book, 2012</ref>
			**100-200mg ampicillin/kg/day IM/IV divided q6 hours
			**First Dose: 25-50mg ampicillin/kg IM/IV x 1 (37.5-75mg Unasyn/kg IM/IV x 1)
			**Max: 1000mg ampicillin (1500mg Unasyn) per DOSE
			*'''Severe'''<ref>Red Book, 2012</ref>
			**200mg ampicillin/kg/day IM/IV divided q6 hours
			**First Dose: 50mg ampicillin/kg IM/IV x 1 (75mg Unasyn/kg IM/IV x 1)
			**Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

			===[[Meningitis]]===
			*400mg ampicillin/kg/day IM/IV divided q6 hours
			*First Dose: 100mg ampicillin/kg IM/IV x 1 (150mg Unasyn/kg IM/IV x 1)
			*Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

			===[[Endocarditis]]===
			*200mg ampicillin/kg/day IM/IV divided q4-6 hours +/- [[gentamicin]] x 4-6 weeks

			===[[SSTI]]===
			*200mg ampicillin/kg/day IM/IV divided q6 hours


	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Ampicillin/Sulbactam]] [[Has Population::Adult]]		{{#ask: [[Has DrugName::Ampicillin/Sulbactam]] [[Has Population::Adult]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

	==Pediatric Dosing==		==Pediatric Dosing==

	===Indications by Disease===		===Indications by Disease===
	{{#ask: [[Has DrugName::Ampicillin/Sulbactam]] [[Has Population::Pediatric]]		{{#ask: [[Has DrugName::Ampicillin/Sulbactam]] [[Has Population::Pediatric]]
	\|?Treats disease=Disease		\|?Treats disease=Disease
	\|?Has Dose=Dose		\|?Has Dose=Dose
	\|?Has Context=Context		\|?Has Context=Context
	\|format=table		\|format=table
	\|limit=50		\|limit=50
	\|mainlabel=-		\|mainlabel=-
	\|headers=show		\|headers=show
	\|sort=Treats disease		\|sort=Treats disease
	}}		}}

Danbot: Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

2026-03-20T01:52:03Z

Replace manual dosing with dynamic SMW tables (Adult + Pediatric)

← Older revision		Revision as of 01:52, 20 March 2026
Line 7:		Line 7:

	==Adult Dosing==		==Adult Dosing==
	===~~General~~===		===Indications by Disease===
	*1.5-~~3g IV/IM q6 hours~~		{{#ask: [[Has DrugName::Ampicillin/Sulbactam]] [[Has Population::Adult]]
	*Max: 12g/day		\|?Treats disease=Disease
			\|?Has Dose=Dose
			\|?Has Context=Context
			\|format=table
			\|limit=50
			\|mainlabel=-
			\|headers=show
			\|sort=Treats disease
			}}

	==~~=[[Bite]] (for Pasteurella multocida Coverage)~~===		==Pediatric Dosing==
	*1.5-3g IM/IV q6 hours		===Indications by Disease===
			{{#ask: [[Has DrugName::Ampicillin/Sulbactam]] [[Has Population::Pediatric]]
	===~~[[Orbital Cellulitis]]~~===		\|?Treats disease=Disease
	*3g IM/IV q6 hours		\|?Has Dose=Dose
			\|?Has Context=Context
	~~===~~[[~~Diabetic Foot]] Osteomyelitis<ref>Lipsky, 2004</ref>===~~		\|format=table
	*3g IM/~~IV q6 hours~~		\|limit=50
			\|mainlabel=-
	~~===[[PID~~]]~~===~~		\|headers=show
	*3g IM/IV q6 hours + [[~~doxycycline~~]]		\|sort=Treats disease
			}}
	=~~==[[Pneumonia]]===~~
	*Aspiration or CAP
	**1.5-3g IM/IV q6 hours
	*Hospital-acquired: 3g IM/IV q6 hours

	===~~[[UTI]], [[Pyelonephritis]]===~~
	*3g IM/IV q6 hours x 14 days

	=~~=Pediatric Dosing (<40kg)==~~
	~~'''Unasyn (ampicillin/sulbactam) is formulated at a 2:1 ratio (3g vial~~ = ~~2g ampicillin + 1g sulbactam)'''~~

	~~===General=~~==
	*'''Mild-moderate'''<ref>Red Book, 2012</ref>
	**100-200mg ampicillin/kg/day IM/IV divided q6 hours
	**First Dose: 25-50mg ampicillin/kg IM/IV x 1 (37.5-~~75mg Unasyn/kg IM/IV x 1)~~
	**Max: 1000mg ampicillin (1500mg Unasyn) per DOSE
	*'''Severe'''<ref>Red Book, 2012</ref>
	**200mg ampicillin/kg/day IM/IV divided q6 hours
	**First Dose: 50mg ampicillin/kg IM/IV x 1 (75mg Unasyn/kg IM/IV x 1)
	**Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

	=~~==[[Meningitis]]===~~
	*400mg ampicillin/kg/day IM/IV divided q6 hours
	*First Dose: 100mg ampicillin/kg IM/IV x 1 (150mg Unasyn/kg IM/IV x 1)
	*Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

	~~===[[Endocarditis]]==~~=
	*200mg ampicillin/kg/day IM/IV divided q4-6 hours +/- [[gentamicin]] x 4-6 weeks

	~~===[[SSTI]]===~~
	*200mg ampicillin/kg/day IM/IV divided q6 hours

	==Special Populations==		==Special Populations==

Rossdonaldson1: /* GeneralRed Book, 2012 */

2026-01-14T21:18:13Z

GeneralRed Book, 2012

← Older revision		Revision as of 21:18, 14 January 2026
Line 34:		Line 34:
	'''Unasyn (ampicillin/sulbactam) is formulated at a 2:1 ratio (3g vial = 2g ampicillin + 1g sulbactam)'''		'''Unasyn (ampicillin/sulbactam) is formulated at a 2:1 ratio (3g vial = 2g ampicillin + 1g sulbactam)'''

	===General~~<ref>Red Book, 2012</ref>~~===		===General===
	*'''Mild-moderate'''		*'''Mild-moderate'''<ref>Red Book, 2012</ref>
	**100-200mg ampicillin/kg/day IM/IV divided q6 hours		**100-200mg ampicillin/kg/day IM/IV divided q6 hours
	**First Dose: 25-50mg ampicillin/kg IM/IV x 1 (37.5-75mg Unasyn/kg IM/IV x 1)		**First Dose: 25-50mg ampicillin/kg IM/IV x 1 (37.5-75mg Unasyn/kg IM/IV x 1)
	**Max: 1000mg ampicillin (1500mg Unasyn) per DOSE		**Max: 1000mg ampicillin (1500mg Unasyn) per DOSE
	*'''Severe'''		*'''Severe'''<ref>Red Book, 2012</ref>
	**200mg ampicillin/kg/day IM/IV divided q6 hours		**200mg ampicillin/kg/day IM/IV divided q6 hours
	**First Dose: 50mg ampicillin/kg IM/IV x 1 (75mg Unasyn/kg IM/IV x 1)		**First Dose: 50mg ampicillin/kg IM/IV x 1 (75mg Unasyn/kg IM/IV x 1)

Rossdonaldson1: /* Pediatric Dosing (<40kg) */

2026-01-14T21:17:26Z

Pediatric Dosing (<40kg)

← Older revision		Revision as of 21:17, 14 January 2026
Line 38:		Line 38:
	**100-200mg ampicillin/kg/day IM/IV divided q6 hours		**100-200mg ampicillin/kg/day IM/IV divided q6 hours
	**First Dose: 25-50mg ampicillin/kg IM/IV x 1 (37.5-75mg Unasyn/kg IM/IV x 1)		**First Dose: 25-50mg ampicillin/kg IM/IV x 1 (37.5-75mg Unasyn/kg IM/IV x 1)
	**Max: 1000mg ampicillin (1500mg Unasyn)		**Max: 1000mg ampicillin (1500mg Unasyn) per DOSE
	*'''Severe'''		*'''Severe'''
	**200mg ampicillin/kg/day IM/IV divided q6 hours		**200mg ampicillin/kg/day IM/IV divided q6 hours
	**First Dose: 50mg ampicillin/kg IM/IV x 1 (75mg Unasyn/kg IM/IV x 1)		**First Dose: 50mg ampicillin/kg IM/IV x 1 (75mg Unasyn/kg IM/IV x 1)
	**Max: 2000mg ampicillin (3000mg Unasyn)		**Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

	===[[Meningitis]]===		===[[Meningitis]]===
	*400mg ampicillin/kg/day IM/IV divided q6 hours		*400mg ampicillin/kg/day IM/IV divided q6 hours
	*First Dose: 100mg ampicillin/kg IM/IV x 1 (150mg Unasyn/kg IM/IV x 1)		*First Dose: 100mg ampicillin/kg IM/IV x 1 (150mg Unasyn/kg IM/IV x 1)
	*Max: 2000mg ampicillin (3000mg Unasyn)		*Max: 2000mg ampicillin (3000mg Unasyn) per DOSE

	===[[Endocarditis]]===		===[[Endocarditis]]===

Ostermayer at 17:45, 18 July 2025

2025-07-18T17:45:33Z

← Older revision		Revision as of 17:45, 18 July 2025
Line 1:		Line 1:
	==General==		==General==
	*Type: Amino-[[Is DrugClass::~~Penicillins~~]]		*Type: Amino-[[Is DrugClass::Penicillin]] with a bacterial [[Is PenicillinType::beta-lactamase inhibitor]]
	*Dosage Forms: powder for solution		*Dosage Forms: powder for solution
	*Dosage Strengths: 1.5g, 3g, 15g		*Dosage Strengths: 1.5g, 3g, 15g

Ostermayer at 17:19, 18 July 2025

2025-07-18T17:19:52Z

← Older revision		Revision as of 17:19, 18 July 2025
Line 1:		Line 1:
	==General==		==General==
	*Type: Amino-[[Penicillins]]		*Type: Amino-[[Is DrugClass::Penicillins]]
	*Dosage Forms: powder for solution		*Dosage Forms: powder for solution
	*Dosage Strengths: 1.5g, 3g, 15g		*Dosage Strengths: 1.5g, 3g, 15g

Mholtz: Text replacement - "==References== " to "==References== "

2017-10-25T21:21:58Z

Text replacement - "==References== <references/>" to "==References== <references/>"

← Older revision		Revision as of 21:21, 25 October 2017
Line 210:		Line 210:

	==References==		==References==

	<references/>		<references/>
	[[Category:Pharmacology]]		[[Category:Pharmacology]]

Humanguy: added dosage form, dosage strength, route of administration

2017-10-11T20:09:45Z

added dosage form, dosage strength, route of administration

← Older revision		Revision as of 20:09, 11 October 2017
Line 1:		Line 1:
	==General==		==General==
	*Type: Amino-[[Penicillins]]		*Type: Amino-[[Penicillins]]
	*Dosage Forms: IM, IV		*Dosage Forms: powder for solution
			*Dosage Strengths: 1.5g, 3g, 15g
			*Routes of Administration: IM, IV
	*Common Trade Names: Unasyn		*Common Trade Names: Unasyn