Alport syndrome - Revision history

Rossdonaldson1: /* Video */

2024-04-10T15:41:39Z

Video

← Older revision		Revision as of 15:41, 10 April 2024
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	==References==		==References==
	<references/>		<references/>

	~~==Video==~~
	~~{{#widget:YouTube\|id=9QWuzj1dcn8}}~~

	[[Category:Renal]]		[[Category:Renal]]

ClaireLewis at 18:05, 16 October 2019

2019-10-16T18:05:18Z

← Older revision		Revision as of 18:05, 16 October 2019
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	==Background==		==Background==
	Alport Syndrome is an autoimmune disorder affecting Type 4 Collagen that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as the disease progresses to [[ESRD]]. The issues are related to a mutation in the COL4A5 (collagen) gene and are inherited in an X-linked pattern.<ref>Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.</ref>		Alport Syndrome is an autoimmune disorder affecting Type 4 Collagen that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with [[hematuria]] and [[proteinuria]] as the disease progresses to [[ESRD]]. The issues are related to a mutation in the COL4A5 (collagen) gene and are inherited in an X-linked pattern.<ref>Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.</ref>

	==Clinical Features==		==Clinical Features==

ClaireLewis at 17:08, 15 October 2019

2019-10-15T17:08:23Z

← Older revision		Revision as of 17:08, 15 October 2019
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	==Clinical Features==		==Clinical Features==
	The degree of clinical features are related to the severity of the organ systems involved. Most common patient will have:		The degree of clinical features are related to the severity of the organ systems involved. Most common patient will have:
	*Lower extremity [[edema]] due to the [[~~hyoalbuimemia~~]]		*Lower extremity [[edema]] due to the [[hypoalbuminemia]]
	*[[Hematuria]]		*[[Hematuria]]
	*[[Hypertension]]		*[[Hypertension]]

Nathanliu91: updated pathophysiology in background, added review video

2019-03-11T15:45:05Z

updated pathophysiology in background, added review video

← Older revision		Revision as of 15:45, 11 March 2019
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	==Background==		==Background==
	~~A syndrome~~ that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as the disease progresses to [[ESRD]]. The issues are related to a mutation in the COL4A5 (collagen) gene and are inherited in an X-linked pattern.<ref>Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.</ref>		Alport Syndrome is an autoimmune disorder affecting Type 4 Collagen that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as the disease progresses to [[ESRD]]. The issues are related to a mutation in the COL4A5 (collagen) gene and are inherited in an X-linked pattern.<ref>Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.</ref>

	==Clinical Features==		==Clinical Features==
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	==References==		==References==
	<references/>		<references/>

			==Video==
			{{#widget:YouTube\|id=9QWuzj1dcn8}}

	[[Category:Renal]]		[[Category:Renal]]

Neil.m.young: Text replacement - "==Diagnosis==" to "==Evaluation=="

2016-07-23T11:20:22Z

Text replacement - "==Diagnosis==" to "==Evaluation=="

← Older revision		Revision as of 11:20, 23 July 2016
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	{{Hematuria DDX}}		{{Hematuria DDX}}

	==~~Diagnosis~~==		==Evaluation==

	==Management==		==Management==

Ostermayer: /* Differential Diagnosis */

2016-06-28T05:43:21Z

Differential Diagnosis

← Older revision		Revision as of 05:43, 28 June 2016
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	==Differential Diagnosis==		==Differential Diagnosis==
			{{Hematuria DDX}}

	==Diagnosis==		==Diagnosis==

Ostermayer: /* Background */

2016-06-28T05:41:36Z

Background

← Older revision		Revision as of 05:41, 28 June 2016
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	==Background==		==Background==
	A syndrome that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as the disease progresses to [[ESRD]]. ~~Most genetic~~ in the COL4A5 gene and are inherited in an X-linked pattern.<ref>Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.</ref>		A syndrome that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as the disease progresses to [[ESRD]]. The issues are related to a mutation in the COL4A5 (collagen) gene and are inherited in an X-linked pattern.<ref>Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.</ref>

	==Clinical Features==		==Clinical Features==

Ostermayer: /* Clinical Features */

2016-06-28T05:38:00Z

Clinical Features

← Older revision		Revision as of 05:38, 28 June 2016
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	==Clinical Features==		==Clinical Features==
			The degree of clinical features are related to the severity of the organ systems involved. Most common patient will have:
			*Lower extremity [[edema]] due to the [[hyoalbuimemia]]
			*[[Hematuria]]
			*[[Hypertension]]
			*[[Hearing Loss]]
			*Visual problems

	==Differential Diagnosis==		==Differential Diagnosis==

Ostermayer at 05:34, 28 June 2016

2016-06-28T05:34:55Z

← Older revision		Revision as of 05:34, 28 June 2016
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	<references/>		<references/>

	[[Renal]]		[[Category:Renal]]

Ostermayer: Created page with "==Background== A syndrome that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as..."

2016-06-28T05:34:27Z

Created page with "==Background== A syndrome that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as..."

New page

==Background==
A syndrome that includes kidney disease, hearing loss, and eye abnormalities. The genetic disease classically also manifests with hematuria and proteinuria as the disease progresses to [[ESRD]]. Most genetic in the COL4A5 gene and are inherited in an X-linked pattern.<ref>Kashtan CE. Familial hematurias: what we know and what we don't. Pediatr Nephrol. 2005 Aug;20(8):1027-35.</ref>

==Clinical Features==

==Differential Diagnosis==

==Diagnosis==

==Management==

==Disposition==

==See Also==

==External Links==

==References==
<references/>

[[Renal]]